NMUR1 Polyclonal Antibody, AbBy Fluor-555 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-11420r-bf555-100uL |
| Product Name | NMUR1 Polyclonal Antibody, AbBy Fluor-555 Conjugated |
| Applications |
FCM
|
| Reactivity | Mouse, Rat |
| Specifications | |
| Conjugation | AbBy Fluor-555 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human NMUR1 |
| Immunogen Range | 31-80/426 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 10316 |
| Swiss Prot | Q9HB89 |
| Subcellular location | Cell membrane |
| Synonyms | FM-3; G protein-coupled receptor 66; G-protein coupled receptor 66; G-protein coupled receptor FM-3; GPR66; Growth hormone secretagogue receptor family Member 3; Neuromedin U Receptor 1; Neuromedin-U receptor 1; NMU-R1; NMUR1; NMUR1_HUMAN. |
| Background | Neuromedin U is a neuropeptide with high activity on smooth muscle. It is widely expressed in gastrointestinal systems and central nervous system (CNS). Peripheral activities of neuromedin U include smooth muscle stimulation, ion transport alterations in the gut and the regulation of local blood flow and adrenocortical function. Neuromedin U receptors 1 and 2 (NMUR1 and NMUR2) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family of proteins. Both NMUR1 and NMUR2 act as receptors for the neuromedin U neuropeptide. NMUR1 is detected in peripheral organs, particularly in urogenital and gastrointestinal systems, with highest levels in testis. It?s expression in CNS is low, but the protein has been detected in cerebellum, hippocampus, dorsal root ganglia and spinal cord. NMUR2 is predominantly detected in central nervous system with highest levels detected in medulla oblongata, spinal cord and thalamus. It may also be detected in testis but has low levels of expression in peripheral tissues. |
| Application Dilution | |
| FCM | 1:20-100 |
Frequently asked questions
Which applications is NMUR1 Polyclonal Antibody, AbBy Fluor-555 Conjugated (bs-11420R-BF555) validated for, and at what dilution?
bs-11420R-BF555 is validated for FCM (1:20-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does NMUR1 Polyclonal Antibody, AbBy Fluor-555 Conjugated (bs-11420R-BF555) react with?
Tested reactivity: Mouse, Rat.
How should bs-11420R-BF555 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise NMUR1 Polyclonal Antibody, AbBy Fluor-555 Conjugated (bs-11420R-BF555)?
KLH conjugated synthetic peptide derived from human NMUR1 Immunogen range: 31-80/426.
What are the excitation and emission wavelengths of the AbBy Fluor-555 conjugate (bs-11420R-BF555)?
AbBy Fluor-555 on bs-11420R-BF555: excitation / emission 553nm/568nm.