| Overview |
| bs-11421R-Biotin |
| NMUR2/GPR-FM4 Polyclonal Antibody, Biotin Conjugated |
| ELISA, IHC-P, IHC-F |
| Human, Cow, Sheep, Pig, Horse, Rabbit |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human NMUR2 |
| 181-230/415 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 56923 |
| Q9GZQ4 |
| Cell membrane |
| FM4; G protein coupled receptor FM 4; G protein coupled receptor TGR 1; G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1; Neuromedin U receptor 2; Neuromedin-U receptor 2; NMU R2; NMU-R2; NMU2R; NMUR2; NMUR2_HUMAN; TGR1 |
| Neuromedin U is a neuropeptide with high activity on smooth muscle. It is widely expressed in gastrointestinal systems and central nervous system (CNS). Peripheral activities of neuromedin U include smooth muscle stimulation, ion transport alterations in the gut and the regulation of local blood flow and adrenocortical function. Neuromedin U receptors 1 and 2 (NMUR1 and NMUR2) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family of proteins. Both NMUR1 and NMUR2 act as receptors for the neuromedin U neuropeptide. NMUR1 is detected in peripheral organs, particularly in urogenital and gastrointestinal systems, with highest levels in testis. It?s expression in CNS is low, but the protein has been detected in cerebellum, hippocampus, dorsal root ganglia and spinal cord. NMUR2 is predominantly detected in central nervous system with highest levels detected in medulla oblongata, spinal cord and thalamus. It may also be detected in testis but has low levels of expression in peripheral tissues. |
| Application Dilution |
| ELISA |
1:500-1000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
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