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EDG8 Polyclonal Antibody, Biotin Conjugated

Applications

  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Mouse

Predicted Reactivity

  • Human
  • Rat
  • Sheep
  • Pig
  • Horse
  • Rabbit
Overview
Catalog # bs-11457R-Biotin
Product Name EDG8 Polyclonal Antibody, Biotin Conjugated
Applications ELISA, IHC-P, IHC-F
Reactivity Mouse
Predicted Reactivity Human, Rat, Sheep, Pig, Horse, Rabbit
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human EDG8
Immunogen Range 1-200/398
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 53637
Swiss Prot Q9H228
Subcellular location Cell membrane
Synonyms EDG8; S1P5; Edg-8; SPPR-1; SPPR-2; Sphingosine 1-phosphate receptor 5; S1P receptor 5; Endothelial differentiation G-protein-coupled receptor 8; Sphingosine 1-phosphate receptor Edg-8; S1P receptor Edg-8; S1PR5
Background Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
Application Dilution
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500