FOXG1 Polyclonal Antibody, Cy7 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-11557R-Cy7-100uL |
| Product Name | FOXG1 Polyclonal Antibody, Cy7 Conjugated |
| Applications |
WB
|
| Reactivity | Rat |
| Predicted Reactivity | Human, Mouse, Dog, Horse, Chicken, Rabbit |
| Specifications | |
| Conjugation | Cy7 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human FOXG1 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Subcellular location | Nucleus |
| Synonyms | BF 1; BF 2; BF-1; BF-2; BF1; BF2 ; Brain factor 1; Brain factor 2; FHKL; FKH2; FKHL1; FKHL2; FKHL2; FKHL3; FKHL4; Forkhead box G1A; Forkhead box G1B; Forkhead box protein G1; Forkhead box protein G1A; Forkhead box protein G1B; Forkhead box protein G1C; Forkhead drosophila homolog like 2; Forkhead like 1; Forkhead like 2; FOXG1_HUMAN. |
| Background | The winged-helix transcriptional repressor (WH) BF-1 gene encodes brain factor 1 (BF-1), also known as foxg1, and is essential for the proliferation of progenitor cells in the cerebral cortex and influences regional patterning in the mammalian telencephalon (14). WH proteins are a family of putative transcriptional regulators with diverse roles in development, and are characterized by a highly conserved DNA binding structure, the WH domain (1,5,6). BF-1 plays a critical role in the development of the cerebral hemispheres of the brain and targeted disruption of the gene leads to severe defects in the development of telencephalic structures, such as the cerebral cortex and basal ganglia (1). The loss of BF-1 results in an accelerated rate of neuronal differentiation and the shortening of the neurogenetic period in the embryonic cerebral cortex (1,7). BF-1 is expressed by E8.5 in telencephalic progenitors (1). It may also regulate the response of cerebral cortical progenitors to environmental cues (1). |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is FOXG1 Polyclonal Antibody, Cy7 Conjugated (bs-11557R-Cy7) validated for, and at what dilution?
bs-11557R-Cy7 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does FOXG1 Polyclonal Antibody, Cy7 Conjugated (bs-11557R-Cy7) react with?
Tested reactivity: Rat. Predicted reactivity (expected from sequence homology but not yet tested): Human, Mouse, Dog, Horse, Chicken, Rabbit.
How should bs-11557R-Cy7 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise FOXG1 Polyclonal Antibody, Cy7 Conjugated (bs-11557R-Cy7)?
KLH conjugated synthetic peptide derived from human FOXG1
What are the excitation and emission wavelengths of the Cy7 conjugate (bs-11557R-Cy7)?
Cy7 on bs-11557R-Cy7: excitation / emission 743nm/767nm.