TAS2R16 Polyclonal Antibody, AbBy Fluor-555 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-11616R-BF555-100uL |
| Product Name | TAS2R16 Polyclonal Antibody, AbBy Fluor-555 Conjugated |
| Applications |
WB
|
| Reactivity | Human |
| Specifications | |
| Conjugation | AbBy Fluor-555 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human TAS2R16 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Subcellular location | Cell membrane |
| Synonyms | TAS2R-16; T2R16; Taste receptor type 2 member 16; T2R16_HUMAN. |
| Background | T2R16 is a 291 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor T2R family. Acting in the oral cavity and the gastrointestinal tract, T2R16 is a gustducin-coupled receptor that is implicated in the perception of bitter compounds. T2R16 mediates responses to certain taste through PLC 2, a phospholipase C selectively expressed in taste tissue, and the calcium-regulated cation channel TRPM5. Expressed in a subset of gustducin-positive taste receptor cells of the tongue and epithelia, T2R16 confers bitter perception of salicin to non-taster mice. The gene that encodes T2R16 consists of 996 bases and maps to human chromosome 7q31. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The Lys-172 polymorphism in T2R16 is associated with genetic susceptibility to alcoholism. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is TAS2R16 Polyclonal Antibody, AbBy Fluor-555 Conjugated (bs-11616R-BF555) validated for, and at what dilution?
bs-11616R-BF555 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does TAS2R16 Polyclonal Antibody, AbBy Fluor-555 Conjugated (bs-11616R-BF555) react with?
Tested reactivity: Human.
How should bs-11616R-BF555 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise TAS2R16 Polyclonal Antibody, AbBy Fluor-555 Conjugated (bs-11616R-BF555)?
KLH conjugated synthetic peptide derived from human TAS2R16
What are the excitation and emission wavelengths of the AbBy Fluor-555 conjugate (bs-11616R-BF555)?
AbBy Fluor-555 on bs-11616R-BF555: excitation / emission 553nm/568nm.