| Overview |
| bs-11819r-bf647-100ul |
| CHRDL1 Polyclonal Antibody, AbBy Fluor-647 Conjugated |
| WB, IF(IHC-P) |
| Human, Mouse, Rat |
| Specifications |
| AbBy Fluor-647 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human CHRDL1 |
| 22-70/450 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 91851 |
| Q9BU40 |
| Secreted |
| CHL; MGC1; MGCN; VOPT; NRLN1; dA141H5.1; Chordin-like protein 1; Neuralin-1; Neurogenesin-1; Ventroptin; CHRDL1 |
| Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation (By similarity). May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development. |
| Application Dilution |
| WB |
1:300-5000 |
| IF(IHC-P) |
1:50-200 |
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