LMCD1 Polyclonal Antibody, PE-Cy5 Conjugated
Applications
Predicted Reactivity
| Overview | |
| Catalog # | bs-11874R-PE-Cy5 |
| Product Name | LMCD1 Polyclonal Antibody, PE-Cy5 Conjugated |
| Applications |
WB
|
| Predicted Reactivity | Human, Dog, Cow, Sheep, Pig, Horse, Rabbit |
| Specifications | |
| Conjugation | PE-Cy5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human LMCD1 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | Dyxin; LIM and cysteine rich domains 1; LIM and cysteine rich domains protein 1; LIM and cysteine-rich domains protein 1; LMCD1_HUMAN. |
| Background | Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T cells signaling pathway. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is LMCD1 Polyclonal Antibody, PE-Cy5 Conjugated (bs-11874R-PE-Cy5) validated for, and at what dilution?
bs-11874R-PE-Cy5 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
How should bs-11874R-PE-Cy5 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise LMCD1 Polyclonal Antibody, PE-Cy5 Conjugated (bs-11874R-PE-Cy5)?
KLH conjugated synthetic peptide derived from human LMCD1
What are the excitation and emission wavelengths of the PE-Cy5 conjugate (bs-11874R-PE-Cy5)?
PE-Cy5 on bs-11874R-PE-Cy5: excitation / emission 488nm/670nm.