| Overview |
| bs-11928r-pe-cy55-100ul |
| PTBP2 Polyclonal Antibody, PE-Cy5.5 Conjugated |
| WB |
| Human, Mouse, Rat |
| Specifications |
| PE-Cy5.5 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human PTBP2 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| brPTB; FLJ34897; MIBP; Neural polypyrimidine tract binding protein; Neurally enriched homolog of PTB; Polypyrimidine tract binding protein 2; PTB; PTB like; PTB like protein; PTBLP; PTBP 2; PTBP-2; Splicing regulator; PTBP2_HUMAN. |
| PTBP-2 is a member of the polypyrimidine tract binding family of proteins. Predominantly expressed in brain, but also found in heart and skeletal muscle, PTBP-2 localizes to the nucleus and contains four RRM (RNA recognition motif) domains. PTBP-2 functions as an RNA-binding protein associated in a complex that is involved in the regulation of exon splicing and the stabilization of mRNAs in the cytoplasm. Six isoforms exist for PTBP-2 due to alternative splicing events. Isoforms 1 and 2 (also known as nPTB1 and nPTB2/PTBPLP-L, respectively) are neuronal-specific. Isoforms 3 and 4 (also known as nPTB3/PTBPLP-L and nPTB4, respectively) are found in non-neuronal tissues, as are isoforms 5 and 6 (also known as nPTB5/nPTB7/PTBPLP-S and nPTB6/nPTB8/PTBPLP-S, respectively). The existence of various isoforms may function to modulate the RNA-binding properties of PTBP-2 |
| Application Dilution |
| WB |
1:300-5000 |
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