GRIK3/GLR7 Polyclonal Antibody, AbBy Fluor-405 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-12007r-bf405 |
| Product Name | GRIK3/GLR7 Polyclonal Antibody, AbBy Fluor-405 Conjugated |
| Applications |
FCM
|
| Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken |
| Specifications | |
| Conjugation | AbBy Fluor-405 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human GRIK3/GLR7 |
| Immunogen Range | 501-600/919 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Subcellular location | Cell membrane |
| Synonyms | EAA5; Excitatory amino acid receptor 5; GLR 7; GLR7; GLU R7; GLUR 7; GluR 7a; GluR-7; GLUR7; GluR7a; Glutamate receptor 7; Glutamate receptor; Glutamate receptor ionotropic kainate 3; GRIK 3; GRIK3; GRIK3_HUMAN; ionotropic kainate 3. |
| Background | Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem, whereas the four epsilon subunits display limited distribution. |
| Application Dilution | |
| FCM | 1:50-200 |
Frequently asked questions
Which applications is GRIK3/GLR7 Polyclonal Antibody, AbBy Fluor-405 Conjugated (bs-12007R-BF405) validated for, and at what dilution?
bs-12007R-BF405 is validated for FCM (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does GRIK3/GLR7 Polyclonal Antibody, AbBy Fluor-405 Conjugated (bs-12007R-BF405) react with?
Tested reactivity: Human. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken.
How should bs-12007R-BF405 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise GRIK3/GLR7 Polyclonal Antibody, AbBy Fluor-405 Conjugated (bs-12007R-BF405)?
KLH conjugated synthetic peptide derived from human GRIK3/GLR7 Immunogen range: 501-600/919.
What are the excitation and emission wavelengths of the AbBy Fluor-405 conjugate (bs-12007R-BF405)?
AbBy Fluor-405 on bs-12007R-BF405: excitation / emission 401nm/421nm.