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GRIK5/KA2 Polyclonal Antibody


  • WB
  • IHC-P
  • IHC-F
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)
  • ICC

Predicted Reactivity

  • Human
  • Mouse
  • Rat
  • Dog
  • Sheep
  • Pig
Catalog # bs-12033R
Product Name GRIK5/KA2 Polyclonal Antibody
Applications WB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), ICC
Predicted Reactivity Human, Mouse, Rat, Dog, Sheep, Pig
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human GRIK5/KA2
Immunogen Range 201-300/980
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Subcellular location Cell membrane
Synonyms EAA 2; EAA2; Excitatory amino acid receptor 2; GluRgamma2; Glutamate receptor; Glutamate receptor KA 2; Glutamate receptor KA-2; Glutamate receptor KA2; Glutamate receptor, ionotropic kainate 5 [Precursor]; Glutamate receptor, ionotropic, kainate 5 gamma 2; Glutamate receptor, ionotropic, kainate 5; GRIK 2; GRIK 5; GRIK2; Grik5; GRIK5_HUMAN; iGlu5; ionotropic kainate 5; KA2; MGC118086.
Background Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of the structurally related subunits GluR-1 to -7, KA1 and KA2. KA1 (also designated EEA1) and KA2 (also designated EEA2) form heteromeric receptors with GluR subunits when coexpressed, forming ion channels with various properties. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500