| Overview |
| bs-12080R-Biotin |
| GABRG3/GABA A Receptor gamma 3 Antibody, Biotin Conjugated |
| WB, ELISA |
| Human |
| Mouse, Rat |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human GABRG3/GABA A Receptor gamma 3 |
| 31-130/467 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| Cell membrane |
| GABAA receptor; GABAA receptor subunit gamma 3; GABR G3; GABRG 3; GABRG3; Gamma aminobutyric acid GABA A receptor gamma 3; Gamma aminobutyric acid A receptor gamma 3; Gamma aminobutyric acid receptor subunit gamma 3; GBRG3_HUMAN. |
| GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R Alpha 1-6, GABAA R Beta 1-3, GABAA R Gamma 1-3, GABAA R Delta, GABAA R Epsilon, GABAA R Zeta 1 and GABAA R Zeta 2. The GABAB family is composed of GABAB R1 Alpha and GABAB R1 Beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action. |
| Application Dilution |
| WB |
1:300-5000 |
| ELISA |
1:500-1000 |
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