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GABRR2 Polyclonal Antibody, Cy3 Conjugated

Applications

  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Predicted Reactivity

  • Human
  • Mouse
  • Rat
  • Dog
  • Cow
  • Sheep
  • Horse
  • Chicken
  • Zebrafish
Overview
Catalog # bs-12085R-Cy3
Product Name GABRR2 Polyclonal Antibody, Cy3 Conjugated
Applications IF(IHC-P), IF(IHC-F), IF(ICC)
Predicted Reactivity Human, Mouse, Rat, Dog, Cow, Sheep, Horse, Chicken, Zebrafish
Specifications
Conjugation Cy3
Host Rabbit
Source KLH conjugated synthetic peptide derived from human GABRR2
Immunogen Range 161-260/465
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Subcellular location Cell membrane
Synonyms GABA receptor Rho 2 subunit; GABAA receptor; GABAA receptor subunit rho-2; GABAC receptor; GABRR 2; Gamma aminobutyric acid receptor rho 2 subunit [Precursor]; Gamma-aminobutyric acid GABA A receptor, rho 2; Gamma-aminobutyric acid receptor subunit rho-2; Rho 2 GABA receptor; GBRR2_HUMAN.
Background Gamma-aminobutyric acid (GABA) receptors are pentameric membrane proteins that operate GABA-gated chloride channels and inhibit neurotransmission in the central nervous system. The rho receptor subunits do not exhibit sensitivity to typical GABA receptor modulators such as bicuculline, hexobarbital, and diazepam. While the rho 1 subunit localizes specifically to the retina, rho 2 expresses in all regions of the brain, though levels were still highest in the retina, implying a role for both subunits in visual pathways.
Application Dilution
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200