GABRR2 Polyclonal Antibody, HRP Conjugated
Applications
Predicted Reactivity
| Overview | |
| Catalog # | bs-12085R-HRP-100uL |
| Product Name | GABRR2 Polyclonal Antibody, HRP Conjugated |
| Applications |
ELISA
IHC-P
IHC-F
|
| Predicted Reactivity | Human, Mouse, Rat, Dog, Cow, Sheep, Horse, Chicken, Zebrafish |
| Specifications | |
| Conjugation | HRP |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human GABRR2 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Subcellular location | Cell membrane |
| Synonyms | GABA receptor Rho 2 subunit; GABAA receptor; GABAA receptor subunit rho-2; GABAC receptor; GABRR 2; Gamma aminobutyric acid receptor rho 2 subunit [Precursor]; Gamma-aminobutyric acid GABA A receptor, rho 2; Gamma-aminobutyric acid receptor subunit rho-2; Rho 2 GABA receptor; GBRR2_HUMAN. |
| Background | Gamma-aminobutyric acid (GABA) receptors are pentameric membrane proteins that operate GABA-gated chloride channels and inhibit neurotransmission in the central nervous system. The rho receptor subunits do not exhibit sensitivity to typical GABA receptor modulators such as bicuculline, hexobarbital, and diazepam. While the rho 1 subunit localizes specifically to the retina, rho 2 expresses in all regions of the brain, though levels were still highest in the retina, implying a role for both subunits in visual pathways. |
| Application Dilution | |
| ELISA | 1:500-1000 |
| IHC-P | 1:200-400 |
| IHC-F | 1:100-500 |
Frequently asked questions
Which applications is GABRR2 Polyclonal Antibody, HRP Conjugated (bs-12085R-HRP) validated for, and at what dilution?
bs-12085R-HRP is validated for ELISA (1:500-1000); IHC-P (1:200-400); IHC-F (1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
How should bs-12085R-HRP be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise GABRR2 Polyclonal Antibody, HRP Conjugated (bs-12085R-HRP)?
KLH conjugated synthetic peptide derived from human GABRR2
