SAPAP2/DLGAP2 Polyclonal Antibody, Cy5 Conjugated


  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)


  • Human
  • Rat

Predicted Reactivity

  • Mouse
Catalog # bs-12139R-Cy5
Product Name SAPAP2/DLGAP2 Polyclonal Antibody, Cy5 Conjugated
Applications IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity Human, Rat
Predicted Reactivity Mouse
Conjugation Cy5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human SAPAP2/DLGAP2
Immunogen Range 251-360/1054
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage Condition Store at 4°C for 12 months.
Subcellular location Cell membrane
Synonyms DAP-2; DAP2; Discs large Drosophila homolog associated protein 2; Discs large homolog associated protein 2; Disks large-associated protein 2; Dlgap2; DLGP2_HUMAN; PSD-95/SAP90-binding protein 2; SAP90/PSD-95-associated protein 2; SAPAP2; hide.
Background A guanylate kinase is a phosphotransferase that produces ADP and GDP from the substrates ATP and GMP. SAPAP2, also known as DAP-2 (Disks large-associated protein 2) and PSD-95/SAP90-binding protein 2, is a 1054 amino acid protein that localizes to the postsynaptic membrane of neuronal cells of the brain and kidney. SAPAP2 likely acts as a signaling molecule which interacts with the human genes DLG1 and DLG4/PSD-95. The gene encoding SAPAP2, DLGAP2, maps to human chromosome 8. Consisting of nearly 146 million base pairs, chromosome 8 encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8.
Application Dilution
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200