| Overview |
| bs-12209R |
| ZNF274 Polyclonal Antibody |
| ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), ICC |
| Human, Mouse, Rat, Rabbit |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human ZNF274 |
| 251-350/653 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 10782 |
| Nucleus |
| SP2114; Zf2; Zinc finger protein 274; Zinc finger protein HFB101; Zinc finger protein with KRAB and SCAN domains 19; Zinc finger protein zfp2; ZKSCAN19; ZN274_HUMAN. |
| Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. A member of the Kr_ppel C2H2-type zinc-finger protein family, ZNF274, also known as Zinc finger protein with KRAB and SCAN domains 19, is a 653 amino acid protein containing five C2H2-type zinc fingers, two KRAB A domains and one SCAN box domain. Predominantly localized to the nucleolus, ZNF274 exhibits transcriptional repressing activity. There are four isoforms of ZNF274 that are produced as a result of alternative splicing events. Although total ZNF274 expression seems to be ubiquitous, the two main isoforms, ZNF274a and ZNF274b, differ slightly in tissue distribution with higher expression of ZNF274a in testis and higher expression of ZNF274b in spleen, ovary, skeletal muscle and thymus. |
| Application Dilution |
| ELISA |
1:500-1000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
| ICC |
1:100-500 |
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