ZNF449 Polyclonal Antibody, Biotin Conjugated

Applications

  • ELISA
  • IHC-P
  • IHC-F

Predicted Reactivity

  • Human
  • Mouse
  • Rat
  • Rabbit
Overview
Catalog # bs-12236R-Biotin
Product Name ZNF449 Polyclonal Antibody, Biotin Conjugated
Applications ELISA, IHC-P, IHC-F
Predicted Reactivity Human, Mouse, Rat, Rabbit
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human ZNF449
Immunogen Range 401-518/518
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 203523
Subcellular location Nucleus
Synonyms FLJ23614; OTTHUMP00000024072; Zinc finger and SCAN domain containing protein 19; Zinc finger and SCAN domain-containing protein 19; Zinc finger protein 449; ZN449_HUMAN; ZNF449; ZSCAN19.
Background Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF449 is a 518 amino acid protein that contains one SCAN box domain and seven C2H2-type zinc fingers. ZNF449 is ubiquitously expressed and localizes to the nucleus. There are three isoforms of ZNF449 that are produced as a result of alternative splicing events.
Application Dilution
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500