Hoxb3 Polyclonal Antibody
Applications
Predicted Reactivity
| Overview | |
| Catalog # | bs-12309R-100uL |
| Product Name | Hoxb3 Polyclonal Antibody |
| Applications |
WB
ELISA
|
| Predicted Reactivity | Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Hoxb3 |
| Immunogen Range | 201-300/431 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 3213 |
| Subcellular location | Nucleus |
| Synonyms | Homeo box 2G; Homeo box B3; Homeobox B3; Homeobox protein Hox-2.7; Homeobox protein Hox-2G; Homeobox protein Hox-B3; Homeobox protein HoxB3; Hox 2.7; HOX 2G; HOX2; Hox2.7; HOX2G; HOXB3; HXB3_HUMAN. |
| Background | HOX genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. There are multiple transcripts of the Hoxb3 gene, and the anterior boundaries of its expression vary at different stages of development. Hoxb3 plays a role in the proliferation and differentiation of both early myeloid and lymphoid developmental pathways. Hoxb3 also has overlapping function in mediating the migration of pharyngeal organ primordia and is expressed in very restricted domains in the future hindbrain. Hoxb6 controls the generation, proliferation and survival of erythroid progenitor cells. The Hoxb6 protein is expressed in the suprabasal layer of the early developing epidermis and throughout the upper layers of late fetal and adult human skin. Hoxb6 is cytoplasmically expressed throughout fetal epidermal development, but displays nuclear expression in normal adult skin. Hoxb6 protein also has nuclear expression in hyperproliferative skin conditions, but appears to be localized in the cytoplasm in basal and squamous cell carcinomas. Hoxb6 genes are also expressed in normal adult lung. |
| Application Dilution | |
| WB | 1:300-5000 |
| ELISA | 1:500-1000 |
Frequently asked questions
Which applications is Hoxb3 Polyclonal Antibody (bs-12309R) validated for, and at what dilution?
bs-12309R is validated for WB (1:300-5000); ELISA (1:500-1000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
How should bs-12309R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Hoxb3 Polyclonal Antibody (bs-12309R)?
KLH conjugated synthetic peptide derived from human Hoxb3 Immunogen range: 201-300/431.