| Overview |
| bs-12386r-apc-cy55-100ul |
| LMX1A Polyclonal Antibody, APC-Cy5.5 Conjugated |
| WB, IF(IHC-P) |
| Human, Mouse, Rat |
| Specifications |
| APC-Cy5.5 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human LMX1A |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 4009 |
| HGNC:6653; LIM homeobox protein 1.1; LIM homeobox transcription factor 1 alpha; LIM homeobox transcription factor 1-alpha; LIM/homeobox protein 1.1; LIM/homeobox protein LMX1A; LMX 1; LMX 1.1; LMX 1A; LMX-1.1; LMX1; LMX1.1; LMX1A; LMX1A_HUMAN; MGC87616. |
| LMX1A belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1A functions in the nucleus as a transcriptional activator to the insulin gene promoter. In the developing embryo, LMX1A is expressed along the neuraxis and leads to the development of the roof plate of the vertebrae. Two isoforms of LMX1A exist due to alternative splicing. Isoform 1 represents the full length protein and is expressed in many tissues including fetal brain, but is absent in heart, liver, spleen and testis. The second isoform, designated LMX1A-4AB, lacks amino acids 1-249 and is expressed in testis. |
| Application Dilution |
| WB |
1:300-5000 |
| IF(IHC-P) |
1:50-200 |
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