SNRNP200 Polyclonal Antibody
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-12657R |
| Product Name | SNRNP200 Polyclonal Antibody |
| Applications |
IHC-P
IHC-F
IF(ICC)
IF
|
| Reactivity | Mouse, Rat |
| Predicted Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human SNRNP200 |
| Immunogen Range | 801-900/2136 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 23020 |
| Swiss Prot | O75643 |
| Synonyms | Activating signal cointegrator 1 complex subunit 3 like 1; ASCC3L1; BRR2; BRR2 homolog; HELIC2; RP33; SNRNP200; U5 200KD; U5 small nuclear ribonucleoprotein 200 kDa helicase; U5 snRNP specific 200 kDa protein. |
| Background | Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. [provided by RefSeq, Mar 2010] |
| Application Dilution | |
| IHC-P | |
| IHC-F | 1:100-500 |
| IF(ICC) | 1:50-200 |
| IF | |
Frequently asked questions
Which applications is SNRNP200 Polyclonal Antibody (bs-12657R) validated for, and at what dilution?
bs-12657R is validated for IHC-P; IHC-F (1:100-500); IF(ICC) (1:50-200); IF. These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does SNRNP200 Polyclonal Antibody (bs-12657R) react with?
Tested reactivity: Mouse, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Human.
How should bs-12657R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise SNRNP200 Polyclonal Antibody (bs-12657R)?
KLH conjugated synthetic peptide derived from human SNRNP200 Immunogen range: 801-900/2136.