ASPP2 Polyclonal Antibody, Cy7 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-1283R-Cy7-100uL |
| Product Name | ASPP2 Polyclonal Antibody, Cy7 Conjugated |
| Applications |
WB
|
| Reactivity | Human, Mouse |
| Predicted Reactivity | Chicken |
| Specifications | |
| Conjugation | Cy7 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human ASPP2 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 7159 |
| Swiss Prot | Q13625 |
| Subcellular location | Nucleus |
| Synonyms | BBP; 53BP2; ASPP2; P53BP2; PPP1R13A; Apoptosis-stimulating of p53 protein 2; Bcl2-binding protein; Renal carcinoma antigen NY-REN-51; Tumor suppressor p53-binding protein 2; p53-binding protein 2; TP53BP2 |
| Background | Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is ASPP2 Polyclonal Antibody, Cy7 Conjugated (bs-1283R-Cy7) validated for, and at what dilution?
bs-1283R-Cy7 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does ASPP2 Polyclonal Antibody, Cy7 Conjugated (bs-1283R-Cy7) react with?
Tested reactivity: Human, Mouse. Predicted reactivity (expected from sequence homology but not yet tested): Chicken.
How should bs-1283R-Cy7 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise ASPP2 Polyclonal Antibody, Cy7 Conjugated (bs-1283R-Cy7)?
KLH conjugated synthetic peptide derived from human ASPP2
What are the excitation and emission wavelengths of the Cy7 conjugate (bs-1283R-Cy7)?
Cy7 on bs-1283R-Cy7: excitation / emission 743nm/767nm.