CD40L Polyclonal Antibody

Applications

  • FCM
  • IHC-P
  • IF(IHC-P)

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-1286R
Product Name CD40L Polyclonal Antibody
Applications FCM, IHC-P, IF(IHC-P)
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CD40L/CD154
Immunogen Range 47-80/261
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Target
Gene ID 959
Swiss Prot P29965
Subcellular location Extracellular
Synonyms IGM; IMD3; TRAP; gp39; CD154; CD4L; HIGM1; T-BAM; TNFSF5; hCD4L; CD4 ligand; CD4-L; T-cell antigen Gp39; TNF-related activation protein; Tumor necrosis factor ligand superfamily member 5; CD4LG
Background Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD4L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.
Application Dilution
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200