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GNAI1 Polyclonal Antibody

Applications

  • ELISA
  • IHC-P
  • IHC-F
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Predicted Reactivity

  • Human
  • Mouse
  • Rat
  • Cow
  • Sheep
  • Pig
  • Zebrafish
Overview
Catalog # bs-13249R
Product Name GNAI1 Polyclonal Antibody
Applications ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
Predicted Reactivity Human, Mouse, Rat, Cow, Sheep, Pig, Zebrafish
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human G protein alpha inhibitor 1
Clonality Polyclonal
Clone # #REF!
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 2770
Subcellular location Cytoplasm, Nucleus, Cell membrane
Synonyms Adenylate cyclase inhibiting G alpha protein; Adenylate cyclase inhibitory protein; Adenylate cyclase-inhibiting G alpha protein; G protein alpha inhibiting 1; G protein alpha inhibiting activity polypeptide 1; Gi; Gi inhibitory G protein; Gi1 protein alpha subunit; GNAI 1; GNAI1; GNAI1_HUMAN; Guanine nucleotide binding protein G protein alpha inhibiting activity polypeptide 1; Guanine nucleotide binding protein alpha inhibiting activity polypeptide 1; Guanine nucleotide binding protein Gi alpha 1 subunit; Guanine nucleotide-binding protein Gi subunit alpha-1; OTTHUMP00000161319; OTTHUMP00000208047.
Background Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.
Application Dilution
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200