| Overview |
| bs-13313R |
| GCHFR Polyclonal Antibody |
| ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), ICC |
| Rat |
| Human, Mouse, Cow, Pig, Chicken |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human GCHFR |
| 21-60/84 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 2644 |
| Cytoplasm, Nucleus, Cell membrane |
| GCHFR; GFRP; GFRP_HUMAN; GTP cyclohydrolase 1 feedback regulatory protein; GTP cyclohydrolase I feedback regulator; GTP cyclohydrolase I feedback regulatory protein; HsT16933; MGC138467; MGC138469; p35. |
| GTP cyclohydrolase I feedback regulatory protein (GFRP) is encoded by the gene GCHFR. GFRP mediates feedback inhibition of GTP cyclohydrolase I activity by tetrahydrobiopterin. GFRP also acts as a mediator for the stimulatory effect of phenylalanine on enzyme activity. L-phenylalanine reverses this inhibition. The molecular weight of GFRP is approximately 9.5kDa although cross-linking experiments have shown that GFRP is usually found as a homodimer or as a pentamer. 15q15. |
| Application Dilution |
| ELISA |
1:500-1000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
| ICC |
1:100-500 |
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