GMPPB Polyclonal Antibody, PE-Cy7 Conjugated
Applications
Predicted Reactivity
| Overview | |
| Catalog # | bs-13461R-PE-Cy7-100uL |
| Product Name | GMPPB Polyclonal Antibody, PE-Cy7 Conjugated |
| Applications |
WB
|
| Predicted Reactivity | Human, Mouse, Rat, Cow, Sheep, Pig, Horse, Rabbit |
| Specifications | |
| Conjugation | PE-Cy7 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human GMPPB |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 29925 |
| Subcellular location | Cytoplasm |
| Synonyms | GDP mannose pyrophosphorylase B; GDP-mannose pyrophosphorylase B; GMPPB; GMPPB_HUMAN; GTP-mannose-1-phosphate guanylyltransferase beta; KIAA1851; Mannose 1 phosphate guanylyltransferase; Mannose-1-phosphate guanyltransferase beta. |
| Background | GMPPB is a 360 amino acid protein that belongs to the transferase hexapeptide repeat family and is involved in protein modification pathways. Functioning as a GDP-mannose pyrophosphorylase, GMPPB enzymatically catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose and a free phosphate, a reaction that is involved in the production of N-linked oligosaccharides. Defects in the gene encoding GMPPB that cause errors in the glycosylation pathway may lead to congenital disorders of glycosylation (CDG). CDGs are multisystemic diseases that often involve both the central and peripheral nervous systems and are often characterized by endocrine and coagulation disorders. GMPPB is expressed as two isoforms due to alternative splicing events. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is GMPPB Polyclonal Antibody, PE-Cy7 Conjugated (bs-13461R-PE-Cy7) validated for, and at what dilution?
bs-13461R-PE-Cy7 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
How should bs-13461R-PE-Cy7 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise GMPPB Polyclonal Antibody, PE-Cy7 Conjugated (bs-13461R-PE-Cy7)?
KLH conjugated synthetic peptide derived from human GMPPB
What are the excitation and emission wavelengths of the PE-Cy7 conjugate (bs-13461R-PE-Cy7)?
PE-Cy7 on bs-13461R-PE-Cy7: excitation / emission 488nm/780nm.