GPR 151 Polyclonal Antibody, FITC Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-13505R-FITC |
| Product Name | GPR 151 Polyclonal Antibody, FITC Conjugated |
| Applications |
WB
IF(IHC-P)
IF(IHC-F)
IF(ICC)
|
| Reactivity | Mouse, Rat |
| Predicted Reactivity | Human, Cow, Sheep, Pig, Horse |
| Specifications | |
| Conjugation | FITC |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human GPR 151 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 134391 |
| Swiss Prot | Q8TDV0 |
| Subcellular location | Cell membrane |
| Synonyms | G protein coupled receptor 151; G protein coupled receptor PGR7; G-protein coupled receptor PGR7; Galanin receptor 4; Galanin receptor like; GALR4; GALRL; GP151_HUMAN; GPCR; GPCR-2037; GPCR2037; GPR151; PGR7; Probable G protein coupled receptor 151; Probable G-protein coupled receptor 151; Putative G protein coupled receptor; GPCR GPR151. |
| Background | GPCR2037 is a G protein-coupled receptor that undergoes weak activation by Galanin and is most abundant in the central nervous system (CNS), where it appears to be critical for development. During embryonal development the expression of GPCR2037 is widespread in the nervous system (dorsal thalamus, striatum, locus coeruleus and hindbrain nuclei). GPCR2037 in the CNS of 7- and 15-day-old mouse embryos can localize to the habenular complex. Low levels of GPCR2037 are detectable in testis, liver, kidney and stomach. In addition to GPCR2037, Galanin mediates its effects through receptor subtypes GALR1, 2 and 3. Galanin ligand exerts anxiolytic actions via GALR receptors under conditions of high stress. Galanin coexists with norepinephrine and serotonin in neural systems that mediate emotion. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |
Frequently asked questions
Which applications is GPR 151 Polyclonal Antibody, FITC Conjugated (bs-13505R-FITC) validated for, and at what dilution?
bs-13505R-FITC is validated for WB (1:300-5000); IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does GPR 151 Polyclonal Antibody, FITC Conjugated (bs-13505R-FITC) react with?
Tested reactivity: Mouse, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Human, Cow, Sheep, Pig, Horse.
How should bs-13505R-FITC be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise GPR 151 Polyclonal Antibody, FITC Conjugated (bs-13505R-FITC)?
KLH conjugated synthetic peptide derived from human GPR 151
What are the excitation and emission wavelengths of the FITC conjugate (bs-13505R-FITC)?
FITC on bs-13505R-FITC: excitation / emission 494nm/518nm.