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GPR146 Polyclonal Antibody, Cy7 Conjugated

Applications

  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Predicted Reactivity

  • Human
Overview
Catalog # bs-13519R-Cy7
Product Name GPR146 Polyclonal Antibody, Cy7 Conjugated
Applications
IF(IHC-P) IF(IHC-F) IF(ICC)
Predicted Reactivity Human
Specifications
Conjugation Cy7
Host Rabbit
Source KLH conjugated synthetic peptide derived from human G protein coupled receptor 146
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 115330
Swiss Prot Q96CH1
Subcellular location Cell membrane
Synonyms G protein coupled receptor 146; G-protein coupled receptor PGR8; GP146_HUMAN; GPR146; PGR8; Probable G-protein coupled receptor 146; GPCR GPR146.
Background G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR146 (G protein-coupled receptor 146), also known as PGR8, is a 333 amino acid multi-pass transmembrane protein that belongs to the G-protein coupled receptor 1 family. Characterized as an orphan receptor for which its endogenous ligand has yet to be identified, GPR146 is thought to play a role in signaling events throughout the cell.
Application Dilution
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Frequently asked questions

Which applications is GPR146 Polyclonal Antibody, Cy7 Conjugated (bs-13519R-Cy7) validated for, and at what dilution?

bs-13519R-Cy7 is validated for IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

How should bs-13519R-Cy7 be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise GPR146 Polyclonal Antibody, Cy7 Conjugated (bs-13519R-Cy7)?

KLH conjugated synthetic peptide derived from human G protein coupled receptor 146

What are the excitation and emission wavelengths of the Cy7 conjugate (bs-13519R-Cy7)?

Cy7 on bs-13519R-Cy7: excitation / emission 743nm/767nm.