ZBTB46 Polyclonal Antibody

$Mouse Liver lysates probed with ZBTB46\/BTBD4 Polyclonal Antibody, Unconjugated (bs-13579R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.$

Mouse Liver lysates probed with ZBTB46\/BTBD4 Polyclonal Antibody, Unconjugated (bs-13579R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.

Applications

WB
ELISA

Reactivity

Mouse

Predicted Reactivity

Human
Rat
Sheep
Horse
Chicken

Overview
Catalog #	bs-13579R
Product Name	ZBTB46 Polyclonal Antibody
Applications	WB, ELISA
Reactivity	Mouse
Predicted Reactivity	Human, Rat, Sheep, Horse, Chicken
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human ZBTB46/BTBD4
Clonality	Polyclonal
Clone #	#REF!
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	140685
Subcellular location	Nucleus
Synonyms	BTB/POZ domain containing protein 4; BTBD4; RINZF; Zinc finger and BTB domain containing 46; Zinc finger and BTB domain containing protein 46; Zinc finger protein 340; ZNF340; ZBT46_HUMAN.
Background	BTBD4 is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.
Application Dilution
WB	1:300-5000
ELISA	1:500-1000