AIF1 Polyclonal Antibody

Applications

  • WB
  • IHC-P
  • IHC-F
  • IF(IHC-P)
  • IF(IHC-F)

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-1363R
Product Name AIF1 Polyclonal Antibody
Applications WB, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F)
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human AIF1
Immunogen Range 116-147/147
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Target
Gene ID 199
Swiss Prot P55008
Subcellular location Cytoplasm, Membrane bound
Synonyms IBA1; IRT1; AIF-1; IRT-1; Allograft inflammatory factor 1; Ionized calcium-binding adapter molecule 1; Protein G1; AIF1; G1
Background Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Application Dilution
WB 1:300-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200