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SSTR3 Polyclonal Antibody, PerCP Conjugated

Applications

  • WB

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-1368R-PerCP
Product Name SSTR3 Polyclonal Antibody, PerCP Conjugated
Applications WB
Reactivity Human, Mouse, Rat
Specifications
Conjugation PerCP
Host Rabbit
Source KLH conjugated synthetic peptide derived from human SSTR3
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 6753
Subcellular location Cytoplasm
Synonyms somatostatin receptor 3; OTTHUMP00000028737; Smstr3; Somatostatin receptor 3; Somatostatin receptor subtype 3; Smstr 3; SS 3R; SS-3-R; SS3-R; SSR-28; SSR3_HUMAN; Sst3; SSTR 3; Somatostatin receptor type 3; SS3R; SSR28; Sst3; SSTR 3; SSTR3.
Background Somatostatin is a tetradecapeptide that is widely distributed in the body. It acts on multiple organs in the body and also functions as a neuropeptide affecting electrical activity of neurons. Somatostatin acts to regulate numerous physiological processes by binding to and activating specific receptors in target tissues. There are five somatostatin receptor subtypes termed SSTR 1 to 5. They are G protein coupled receptors characterized by seven transmembrane helices with an extracellular amino terminal domain and an intracellular carboxy terminus. These receptors are activated by somatostatin secreted by nerve and endocrine cells and function in the regulation of numerous physiological processes such as the secretion of insulin, glucagon and growth hormone. The SSTRs also play a role in cell growth induced by neuronal excitation in both the central and peripheral nervous system. Somatostatin receptors have been implicated in numerous diseases ranging from Alzheimer's to cancers of the gastrointestinal tract, breast, prostate, and pituitary.
Application Dilution
WB 1:500-2000