APEX1 Polyclonal Antibody, PerCP Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-1406R-PerCP-100uL |
| Product Name | APEX1 Polyclonal Antibody, PerCP Conjugated |
| Applications |
WB
|
| Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Dog, Cow, Pig, Chicken |
| Specifications | |
| Conjugation | PerCP |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human APEX1 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 328 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | mitochondrial; AP endonuclease 1; Ape1; AP endonuclease class I; AP lyase; APE 1; APE; APE-1; APEN; APEX 1; APEX; APEX nuclease multunctional DNA repair enzyme 1; Apex nuclease 1; APEX nuclease; APEX1; APEX1_HUMAN; Apurinic endonuclease; Apurinic-apyrimidinic endonuclease 1; Apurinic/apyrimidinic abasic endonuclease; Apurinic/apyrimidinic endonuclease 1; Apurinic/apyrimidinic exonuclease; APX; BAP1; Deoxyribonuclease apurinic or apyrimidinic; DNA apurinic or apyrimidinic site lyase; DNA-apurinic or apyrimidinic site lyase; DNA-apurinic or apyrimidinic site lyase, mitochondrial; EC 4.2.99.18; HAP 1; HAP1; Human Apurinic endonuclease 1; Apurinic/Apyrimidic eEndonuclease 1; MGC139790; Multunctional DNA repair enzyme; Redox effector factor 1; Redox factor 1; Redox factor-1; REF 1; REF 1 protein; REF-1; REF1; REF1 protein. |
| Background | Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq]. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is APEX1 Polyclonal Antibody, PerCP Conjugated (bs-1406R-PerCP) validated for, and at what dilution?
bs-1406R-PerCP is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does APEX1 Polyclonal Antibody, PerCP Conjugated (bs-1406R-PerCP) react with?
Tested reactivity: Human. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Rat, Dog, Cow, Pig, Chicken.
How should bs-1406R-PerCP be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise APEX1 Polyclonal Antibody, PerCP Conjugated (bs-1406R-PerCP)?
KLH conjugated synthetic peptide derived from human APEX1
What are the excitation and emission wavelengths of the PerCP conjugate (bs-1406R-PerCP)?
PerCP on bs-1406R-PerCP: excitation / emission 482nm/677nm.