DEF8 Polyclonal Antibody, Cy3 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-14241R-Cy3-100uL |
| Product Name | DEF8 Polyclonal Antibody, Cy3 Conjugated |
| Applications |
WB
IF
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Cy3 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human DEF8 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 54849 |
| Swiss Prot | Q6ZN54 |
| Synonyms | DEF-8; Def8; Def 8; DEFI8_HUMAN; Differentially expressed in FDCP 8 homolog; FLJ20186; MGC104349. |
| Background | DEF8 is a 512 amino acid protein that is expressed at highest levels in peripheral leukocytes. It is expressed as five isoforms as a result of alternative splicing events. The gene encoding DEF8 maps to chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition that may involve the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. |
| Application Dilution | |
| WB | |
| IF | ICC1:50-200 |
Frequently asked questions
Which applications is DEF8 Polyclonal Antibody, Cy3 Conjugated (bs-14241R-Cy3) validated for, and at what dilution?
bs-14241R-Cy3 is validated for WB; IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does DEF8 Polyclonal Antibody, Cy3 Conjugated (bs-14241R-Cy3) react with?
Tested reactivity: Human, Mouse, Rat.
How should bs-14241R-Cy3 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise DEF8 Polyclonal Antibody, Cy3 Conjugated (bs-14241R-Cy3)?
KLH conjugated synthetic peptide derived from human DEF8
What are the excitation and emission wavelengths of the Cy3 conjugate (bs-14241R-Cy3)?
Cy3 on bs-14241R-Cy3: excitation / emission 512,550nm/570,615nm.