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DEXI Polyclonal Antibody, APC-Cy7 Conjugated

Applications

  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Mouse

Predicted Reactivity

  • Human
  • Rat
  • Cow
  • Sheep
  • Horse
Overview
Catalog # bs-14283R-APC-Cy7
Product Name DEXI Polyclonal Antibody, APC-Cy7 Conjugated
Applications
IF(IHC-P) IF(IHC-F) IF(ICC)
Reactivity Mouse
Predicted Reactivity Human, Rat, Cow, Sheep, Horse
Specifications
Conjugation APC-Cy7
Host Rabbit
Source KLH conjugated synthetic peptide derived from human DEXI
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 28955
Swiss Prot O95424
Subcellular location Cytoplasm, Nucleus
Synonyms Dexamethasone-induced protein; DEXI; DEXI_HUMAN; MYLE; Protein MYLE.
Background DEXI is a 95 amino acid protein belonging to the DEXI family. Induced by dexamethasone, DEXI is expressed in brain, liver, pancreas, placenta and lung, with highest levels in heart. DEXI is also up-regulated in emphysematous lung compared to normal lung. The gene encoding DEXI maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition.
Application Dilution
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Frequently asked questions

Which applications is DEXI Polyclonal Antibody, APC-Cy7 Conjugated (bs-14283R-APC-Cy7) validated for, and at what dilution?

bs-14283R-APC-Cy7 is validated for IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does DEXI Polyclonal Antibody, APC-Cy7 Conjugated (bs-14283R-APC-Cy7) react with?

Tested reactivity: Mouse. Predicted reactivity (expected from sequence homology but not yet tested): Human, Rat, Cow, Sheep, Horse.

How should bs-14283R-APC-Cy7 be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise DEXI Polyclonal Antibody, APC-Cy7 Conjugated (bs-14283R-APC-Cy7)?

KLH conjugated synthetic peptide derived from human DEXI

What are the excitation and emission wavelengths of the APC-Cy7 conjugate (bs-14283R-APC-Cy7)?

APC-Cy7 on bs-14283R-APC-Cy7: excitation / emission 650nm/780nm.