EXOC3L2 Polyclonal Antibody, AbBy Fluor-488 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-14660R-BF488 |
| Product Name | EXOC3L2 Polyclonal Antibody, AbBy Fluor-488 Conjugated |
| Applications |
IF(IHC-P)
IF(IHC-F)
IF(ICC)
|
| Reactivity | Rat |
| Predicted Reactivity | Human, Mouse, Cow |
| Specifications | |
| Conjugation | AbBy Fluor-488 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human EXOC3L2 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 90332 |
| Swiss Prot | Q2M3D2 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | Exocyst complex component 3 like; Exocyst complex component 3 like protein 2; FLJ36147; EX3L2_HUMAN; HBV X transactivated gene 7 protein; HBV XAg transactivated protein 7; MGC16332; OTTHUMP00000207128; OTTMUSP00000045827; Protein 7 transactivated by hepatitis B virus X antigen (HBxAg); XTP7. |
| Background | Exocytosis is crucial in membrane trafficking and it mediates hormone and neurotransmitter secretion out of the cell, as well as the incorporation of membrane proteins and lipids to the plasma membrane. It is crucial for cell-cell communication, cell growth and cell polarity. The exocyst complex is a multi-protein complex that consists of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70 and Exo84, and is essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. The exocyst complex inhibits tubulin polymerization in vitro, suggesting that the exocyst complex is important for modulating the microtubule dynamics that underlie exocytosis. ExoC3L2 (Exocyst complex component 3-like protein 2), also known as HBV X-transactivated gene 7 protein, is a 409 amino acid protein that is related to the Sec6 component of the exocyst complex. |
| Application Dilution | |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |
Frequently asked questions
Which applications is EXOC3L2 Polyclonal Antibody, AbBy Fluor-488 Conjugated (bs-14660R-BF488) validated for, and at what dilution?
bs-14660R-BF488 is validated for IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does EXOC3L2 Polyclonal Antibody, AbBy Fluor-488 Conjugated (bs-14660R-BF488) react with?
Tested reactivity: Rat. Predicted reactivity (expected from sequence homology but not yet tested): Human, Mouse, Cow.
How should bs-14660R-BF488 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise EXOC3L2 Polyclonal Antibody, AbBy Fluor-488 Conjugated (bs-14660R-BF488)?
KLH conjugated synthetic peptide derived from human EXOC3L2
What are the excitation and emission wavelengths of the AbBy Fluor-488 conjugate (bs-14660R-BF488)?
AbBy Fluor-488 on bs-14660R-BF488: excitation / emission 499nm/519nm.