CD177 Polyclonal Antibody


  • WB
  • IHC-P


  • Human
  • Mouse
  • Rat
Catalog # bs-1482R
Product Name CD177 Polyclonal Antibody
Applications WB, IHC-P
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from rat CD177
Immunogen Range 521-650/818
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID 499099
Swiss Prot D3ZCH9
Subcellular location Cell membrane
Synonyms NB1 GP;PRV-1;HNA-2a;NB1 glycoprotein;Neutrophil Glycoprotein NB1; RGD1562941; CD177 antigen; Polycythemia rubra vera protein 1; PRV-1; NB1 glycoprotein; NB1 GP; Human neutrophil alloantigen 2a; HNA-2a; CD177; CD177_HUMAN; CD177_MOUSE.
Background Cd177 (NP1), a glycosyl phosphatidylinositol (GPI) linked N glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia and analyses showed cell surface expression of a 60 kDa protein, 14 kDa greater than the predicted size, probably due to the presence of 3 potential N glycosylation sites. Immunohistochemistry demonstrated expression in bone marrow early erythroblasts, megakaryocytes, promyelocytes, and myelocytes. The neutrophil NB1 antigen (CD177) is expressed by 97% of the caucasian population. against NB1 can be involved in neonatal alloimmune neutropenia (NAN).
Application Dilution
WB 1:300-5000
IHC-P 1:200-400