RBBP6/P2P-R Polyclonal Antibody, FITC Conjugated

Applications

  • WB
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Mouse
  • Rat

Predicted Reactivity

  • Human
Overview
Catalog # bs-1483R-FITC
Product Name RBBP6/P2P-R Polyclonal Antibody, FITC Conjugated
Applications WB, IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity Mouse, Rat
Predicted Reactivity Human
Specifications
Conjugation FITC
Host Rabbit
Source KLH conjugated synthetic peptide derived from human P2PR
Immunogen Range 2-150/1792
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 5930
Swiss Prot Q7Z6E9
Subcellular location Cytoplasm, Nucleus
Synonyms PACT; MY038; P2P-R; RBQ-1; SNAMA; E3 ubiquitin-protein ligase RBBP6; Proliferation potential-related protein; Protein P2P-R; Retinoblastoma-binding Q protein 1; Retinoblastoma-binding protein 6; p53-associated cellular protein of testis; RBBP6; P2PR; RBQ1
Background E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome. May play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53; may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200