Bim Polyclonal Antibody

$Formalin-fixed and paraffin embedded mouse intestine tissue labeled with Anti BIM\/BCL2L11 Polyclonal Antibody, Unconjugated (bs-1488R) at 1:200 followed by conjugation to the secondary antibody and DAB staining$

Formalin-fixed and paraffin embedded mouse intestine tissue labeled with Anti BIM\/BCL2L11 Polyclonal Antibody, Unconjugated (bs-1488R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Applications

WB
ELISA
FCM
IHC-P

Reactivity

Human
Rat

Predicted Reactivity

Mouse
Dog
Cow
Sheep
Pig
Horse

Overview
Catalog #	bs-1488R
Product Name	Bim Polyclonal Antibody
Applications	WB, ELISA, FCM, IHC-P
Reactivity	Human, Rat
Predicted Reactivity	Mouse, Dog, Cow, Sheep, Pig, Horse
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human of human Bim
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	10018
Swiss Prot	O43521
Subcellular location	Cytoplasm, Cell membrane
Synonyms	BAM; BIM; BOD; Bcl-2-like protein 11; Bcl2-L-11; Bcl2-interacting mediator of cell death; BCL2L11
Background	Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.
Application Dilution
WB	1:300-5000
ELISA	1:500-1000
FCM	1:20-100
IHC-P	1:200-400