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PIEZO1/2 Polyclonal Antibody, Biotin Conjugated

Applications

  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Mouse

Predicted Reactivity

  • Human
  • Rat
  • Dog
  • Cow
  • Sheep
Overview
Catalog # bs-14991R-Biotin
Product Name PIEZO1/2 Polyclonal Antibody, Biotin Conjugated
Applications ELISA, IHC-P, IHC-F
Reactivity Mouse
Predicted Reactivity Human, Rat, Dog, Cow, Sheep
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human PIEZO1
Immunogen Range 2451-2521/2521
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 9780
Swiss Prot Q92508
Subcellular location Cytoplasm, Cell membrane
Synonyms Piezo-type mechanosensitive ion channel component 1; Piezo-type mechanosensitive ion channel component 2; PIEZO1; PIEZO2; Mib; C18orf30; C18orf58; FAM38B; FAM38A; KIAA0233
Background Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains. 'Piezo' comes from the Greek 'piesi,' meaning 'pressure.' The FAM38A gene encodes PIEZO1, a protein that induces mechanically activated (MA) currents in various cell types. PIEZO2 Component of a mechanosensitive channel required for rapidly adapting mechanically activated (MA) currents. Required for Merkel-cell mechanotransduction. Plays a major role in light-touch mechanosensation
Application Dilution
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500