FAM43B Polyclonal Antibody
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-14993R |
| Product Name | FAM43B Polyclonal Antibody |
| Applications |
IHC-P
IHC-F
IF(ICC)
IF
|
| Reactivity | Mouse, Rat |
| Predicted Reactivity | Human, Pig |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human FAM43B |
| Immunogen Range | 151-250/329 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 163933 |
| Swiss Prot | Q6ZT52 |
| Synonyms | Family with sequence similarity 43 member B; FA43B_HUMAN; Protein FAM43B. |
| Background | Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The FAM43B gene product has been provisionally designated FAM43B pending further characterization. |
| Application Dilution | |
| IHC-P | |
| IHC-F | 1:100-500 |
| IF(ICC) | 1:50-200 |
| IF | |
Frequently asked questions
Which applications is FAM43B Polyclonal Antibody (bs-14993R) validated for, and at what dilution?
bs-14993R is validated for IHC-P; IHC-F (1:100-500); IF(ICC) (1:50-200); IF. These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does FAM43B Polyclonal Antibody (bs-14993R) react with?
Tested reactivity: Mouse, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Human, Pig.
How should bs-14993R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise FAM43B Polyclonal Antibody (bs-14993R)?
KLH conjugated synthetic peptide derived from human FAM43B Immunogen range: 151-250/329.