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C9orf173 Polyclonal Antibody, APC-Cy5.5 Conjugated

Applications

  • WB

Reactivity

  • Mouse

Predicted Reactivity

  • Human
  • Rat
  • Dog
Overview
Catalog # bs-15321R-APC-Cy5.5
Product Name C9orf173 Polyclonal Antibody, APC-Cy5.5 Conjugated
Applications
WB
Reactivity Mouse
Predicted Reactivity Human, Rat, Dog
Specifications
Conjugation APC-Cy5.5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human C9orf173
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 441476
Subcellular location Cytoplasm, Nucleus
Synonyms C9orf173; Chromosome 9 open reading frame 173; CI173_HUMAN; Uncharacterized protein C9orf173.
Background C9orf173 (chromosome 9 open reading frame 173) is a 389 amino acid protein that exists as four alternatively spliced isoforms. The gene encoding C9orf173 maps to human chromosome 9q34.3. Chromosome 9 consists of about 145 million bases, represents 4% of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
Application Dilution
WB 1:300-5000

Frequently asked questions

Which applications is C9orf173 Polyclonal Antibody, APC-Cy5.5 Conjugated (BS-15321R-APC-CY5-5) validated for, and at what dilution?

BS-15321R-APC-CY5-5 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does C9orf173 Polyclonal Antibody, APC-Cy5.5 Conjugated (BS-15321R-APC-CY5-5) react with?

Tested reactivity: Mouse. Predicted reactivity (expected from sequence homology but not yet tested): Human, Rat, Dog.

How should BS-15321R-APC-CY5-5 be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise C9orf173 Polyclonal Antibody, APC-Cy5.5 Conjugated (BS-15321R-APC-CY5-5)?

KLH conjugated synthetic peptide derived from human C9orf173

What are the excitation and emission wavelengths of the APC-Cy5.5 conjugate (BS-15321R-APC-CY5-5)?

APC-Cy5.5 on BS-15321R-APC-CY5-5: excitation / emission 650nm/694nm.