C9orf173 Polyclonal Antibody, PE Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-15321R-PE |
| Product Name | C9orf173 Polyclonal Antibody, PE Conjugated |
| Applications |
WB
|
| Reactivity | Mouse |
| Predicted Reactivity | Human, Rat, Dog |
| Specifications | |
| Conjugation | PE |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human C9orf173 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 441476 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | C9orf173; Chromosome 9 open reading frame 173; CI173_HUMAN; Uncharacterized protein C9orf173. |
| Background | C9orf173 (chromosome 9 open reading frame 173) is a 389 amino acid protein that exists as four alternatively spliced isoforms. The gene encoding C9orf173 maps to human chromosome 9q34.3. Chromosome 9 consists of about 145 million bases, represents 4% of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is C9orf173 Polyclonal Antibody, PE Conjugated (bs-15321R-PE) validated for, and at what dilution?
bs-15321R-PE is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does C9orf173 Polyclonal Antibody, PE Conjugated (bs-15321R-PE) react with?
Tested reactivity: Mouse. Predicted reactivity (expected from sequence homology but not yet tested): Human, Rat, Dog.
How should bs-15321R-PE be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise C9orf173 Polyclonal Antibody, PE Conjugated (bs-15321R-PE)?
KLH conjugated synthetic peptide derived from human C9orf173
What are the excitation and emission wavelengths of the PE conjugate (bs-15321R-PE)?
PE on bs-15321R-PE: excitation / emission 496,564nm/578nm.