HERC2 Polyclonal Antibody, Biotin Conjugated

Applications

  • ELISA
  • IHC-P
  • IHC-F

Predicted Reactivity

  • Human
  • Mouse
  • Rat
  • Dog
  • Cow
  • Sheep
  • Pig
  • Horse
Overview
Catalog # bs-15460R-Biotin
Product Name HERC2 Polyclonal Antibody, Biotin Conjugated
Applications ELISA, IHC-P, IHC-F
Predicted Reactivity Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human HERC2
Immunogen Range 51-200/4834
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 8924
Swiss Prot O95714
Subcellular location Cytoplasm, Nucleus
Synonyms HECT domain and RCC1 like domain containing protein 2; Hect domain and RLD 2; jdf2; p528; SHEP1; HERC2_HUMAN; E3 ubiquitin-protein ligase HERC2; HECT-type E3 ubiquitin transferase HERC2
Background HERC2 is a belongs to the HERC gene family that encodes a group of unusually large proteins, which contain multiple structural domains. All members have at least 1 copy of an N-terminal region showing homology to the cell cycle regulator RCC1 and a C-terminal HECT (homologous to E6-AP C terminus) domain found in a number of E3 ubiquitin protein ligases. Genetic variations in this gene are associated with skin/hair/eye pigmentation variability. Multiple pseudogenes of this gene are located on chromosomes 15 and 16.
Application Dilution
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500