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INT11/CPSF3L Polyclonal Antibody, PE-Cy5 Conjugated

Applications

  • WB

Reactivity

  • Mouse
  • Rat

Predicted Reactivity

  • Human
  • Horse
  • Zebrafish
  • Orangutan
  • Rhesus monkey
  • Gorilla
  • Opossum
  • Elephant
Overview
Catalog # bs-16677R-PE-Cy5
Product Name INT11/CPSF3L Polyclonal Antibody, PE-Cy5 Conjugated
Applications
WB
Reactivity Mouse, Rat
Predicted Reactivity Human, Horse, Zebrafish, Orangutan, Rhesus monkey, Gorilla, Opossum, Elephant
Specifications
Conjugation PE-Cy5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human INT11
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 54973
Swiss Prot Q5TA45
Subcellular location Cytoplasm, Nucleus
Synonyms RC68; INT11; RC-68; INTS11; CPSF73L; Integrator complex subunit 11; Cleavage and polyadenylation-specific factor 3-like protein; CPSF3-like protein; Protein related to CPSF subunits of 68 kDa; CPSF3L
Background Catalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage.
Application Dilution
WB 1:300-5000

Frequently asked questions

Which applications is INT11/CPSF3L Polyclonal Antibody, PE-Cy5 Conjugated (bs-16677R-PE-Cy5) validated for, and at what dilution?

bs-16677R-PE-Cy5 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does INT11/CPSF3L Polyclonal Antibody, PE-Cy5 Conjugated (bs-16677R-PE-Cy5) react with?

Tested reactivity: Mouse, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Human, Horse, Zebrafish, Orangutan, Rhesus monkey, Gorilla, Opossum, Elephant.

How should bs-16677R-PE-Cy5 be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise INT11/CPSF3L Polyclonal Antibody, PE-Cy5 Conjugated (bs-16677R-PE-Cy5)?

KLH conjugated synthetic peptide derived from human INT11

What are the excitation and emission wavelengths of the PE-Cy5 conjugate (bs-16677R-PE-Cy5)?

PE-Cy5 on bs-16677R-PE-Cy5: excitation / emission 488nm/670nm.