gamma catenin Polyclonal Antibody, AbBy Fluor-350 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-1720R-BF350-100uL |
| Product Name | gamma catenin Polyclonal Antibody, AbBy Fluor-350 Conjugated |
| Applications |
WB
IF(IHC-P)
IF(IHC-F)
IF(ICC)
|
| Specificity | This antibody may have minor cross-reactivity with catenin beta-1 based upon 75% non-contiguous sequence similarity. |
| Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit |
| Specifications | |
| Conjugation | AbBy Fluor-350 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Cateninma gamma |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 3728 |
| Swiss Prot | P14923 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | DP3; PDGB; PKGB; CTNNG; DPIII; ARVD12; Junction plakoglobin; Catenin gamma; Desmoplakin III; Desmoplakin-3; JUP |
| Background | Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity). |
| Application Dilution | |
| WB | 1:300-5000 |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |
Frequently asked questions
Which applications is gamma catenin Polyclonal Antibody, AbBy Fluor-350 Conjugated (bs-1720R-BF350) validated for, and at what dilution?
bs-1720R-BF350 is validated for WB (1:300-5000); IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does gamma catenin Polyclonal Antibody, AbBy Fluor-350 Conjugated (bs-1720R-BF350) react with?
Tested reactivity: Human. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit.
How should bs-1720R-BF350 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise gamma catenin Polyclonal Antibody, AbBy Fluor-350 Conjugated (bs-1720R-BF350)?
KLH conjugated synthetic peptide derived from human Cateninma gamma
What are the excitation and emission wavelengths of the AbBy Fluor-350 conjugate (bs-1720R-BF350)?
AbBy Fluor-350 on bs-1720R-BF350: excitation / emission 346nm/442nm.