phospho-HIRA (Thr555) Polyclonal Antibody, APC Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-17406R-APC |
| Product Name | phospho-HIRA (Thr555) Polyclonal Antibody, APC Conjugated |
| Applications |
WB
|
| Reactivity | Human, Mouse |
| Predicted Reactivity | Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit |
| Specifications | |
| Conjugation | APC |
| Host | Rabbit |
| Source | KLH conjugated synthesised phosphopeptide derived from human HIRA around the phosphorylation site of Thr555 |
| Modification Site | Thr555 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 7290 |
| Swiss Prot | P54198 |
| Subcellular location | Nucleus |
| Synonyms | HIRA (phospho T555); p-HIRA (phospho T555); DGCR1; DGGR 1; DGGR1; DiGeorge critical region gene 1; HIR; HIR histone cell cycle regulation defective homolog A; HIRA; HIRA protein; HIRA_HUMAN; Protein HIRA; TUP 1; TUP1; TUP1 like enhancer of split protein 1; TUP1-like enhancer of split protein 1; TUPLE 1; TUPLE1. |
| Background | This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008] |
| Application Dilution | |
| WB | |
Frequently asked questions
Which applications is phospho-HIRA (Thr555) Polyclonal Antibody, APC Conjugated (bs-17406R-APC) validated for, and at what dilution?
bs-17406R-APC is validated for WB.
Which species does phospho-HIRA (Thr555) Polyclonal Antibody, APC Conjugated (bs-17406R-APC) react with?
Tested reactivity: Human, Mouse. Predicted reactivity (expected from sequence homology but not yet tested): Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit.
How should bs-17406R-APC be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise phospho-HIRA (Thr555) Polyclonal Antibody, APC Conjugated (bs-17406R-APC)?
KLH conjugated synthesised phosphopeptide derived from human HIRA around the phosphorylation site of Thr555