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GATA4 Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • ELISA
  • IHC-P

Reactivity

  • Human
  • Mouse
  • Rat

Predicted Reactivity

  • Dog
  • Cow
  • Pig
  • Chicken
  • Rabbit
Overview
Catalog # bs-1778R-Biotin
Product Name GATA4 Polyclonal Antibody, Biotin Conjugated
Applications WB, ELISA, IHC-P
Specificity May also interact with GATA-5, GATA-6
Reactivity Human, Mouse, Rat
Predicted Reactivity Dog, Cow, Pig, Chicken, Rabbit
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human GATA-4
Immunogen Range 261-360/442
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 2626
Swiss Prot P43694
Subcellular location Nucleus
Synonyms TOF; ASD2; VSD1; TACHD; Transcription factor GATA-4; GATA-binding factor 4; GATA4
Background Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400