IRF9 Polyclonal Antibody

$Formalin-fixed and paraffin embedded human kidney tissue labeled with Rabbit Anti-IRF9 Polyclonal Antibody, Unconjugated (bs-18169R) at 1:200 followed by conjugation to the secondary antibody and DAB staining \\n$

Formalin-fixed and paraffin embedded human kidney tissue labeled with Rabbit Anti-IRF9 Polyclonal Antibody, Unconjugated (bs-18169R) at 1:200 followed by conjugation to the secondary antibody and DAB staining \\n

Formalin-fixed and paraffin embedded Human lung carcinoma tissue labeled with Anti-IRF9 Polyclonal Antibody, Unconjugated (bs-18169R) at 1:300 followed by conjugation to the secondary antibody and DAB staining

Formalin-fixed and paraffin embedded Human lung carcinoma labeled with Anti-IRF9 Polyclonal Antibody, Unconjugated (bs-18169R) at 1:300 followed by conjugation to the secondary antibody and DAB staining

Applications

WB
ELISA
IHC-P
IHC-F
IF(IHC-P)
IF(IHC-F)
IF(ICC)
ICC

Reactivity

Human

Overview
Catalog #	bs-18169R
Product Name	IRF9 Polyclonal Antibody
Applications	WB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), ICC
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human IRF9
Immunogen Range	101-200/393
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	10379
Swiss Prot	Q00978
Subcellular location	Cytoplasm, Nucleus
Synonyms	p48; IRF-9; ISGF3; ISGF3G; Interferon regulatory factor 9; IFN-alpha-responsive transcription factor subunit; ISGF3 p48 subunit; Interferon-stimulated gene factor 3 gamma; ISGF-3 gamma; Transcriptional regulator ISGF3 subunit gamma; IRF9
Background	Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Application Dilution
WB	1:300-5000
ELISA	1:500-1000
IHC-P	1:200-400
IHC-F	1:100-500
IF(IHC-P)	1:50-200
IF(IHC-F)	1:50-200
IF(ICC)	1:50-200
ICC	1:100-500

Applications

Reactivity

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