| Overview |
| bs-1849R-BF488 |
| Midkine Polyclonal Antibody, AbBy Fluor-488 Conjugated |
| IF(IHC-P) |
| Human, Rat |
| Mouse, Dog, Cow, Horse, Fruit Fly |
| Specifications |
| AbBy Fluor-488 |
| Rabbit |
| KLH conjugated synthetic peptide derived from mouse Midkine |
| Polyclonal |
| #REF! |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 4192 |
| P21741 |
| Secreted |
| MK; ARAP; NEGF2; Midkine; Amphiregulin-associated protein; Midgestation and kidney protein; Neurite outgrowth-promoting factor 2; Neurite outgrowth-promoting protein; MDK; MK1 |
| Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development (By similarity). |
| Application Dilution |
| IF(IHC-P) |
|