Midkine Polyclonal Antibody, Biotin Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-1849R-Biotin |
| Product Name | Midkine Polyclonal Antibody, Biotin Conjugated |
| Applications |
IHC-P
|
| Reactivity | Human, Rat |
| Predicted Reactivity | Mouse, Dog, Cow, Horse, Fruit Fly |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from mouse Midkine |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C for 12 months. |
| Target | |
| Gene ID | 4192 |
| Swiss Prot | P21741 |
| Subcellular location | Secreted |
| Synonyms | MK; ARAP; NEGF2; Midkine; Amphiregulin-associated protein; Midgestation and kidney protein; Neurite outgrowth-promoting factor 2; Neurite outgrowth-promoting protein; MDK; MK1 |
| Background | Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development (By similarity). |
| Application Dilution | |
| IHC-P | |
Frequently asked questions
Which applications is Midkine Polyclonal Antibody, Biotin Conjugated (bs-1849R-Biotin) validated for, and at what dilution?
bs-1849R-Biotin is validated for IHC-P.
Which species does Midkine Polyclonal Antibody, Biotin Conjugated (bs-1849R-Biotin) react with?
Tested reactivity: Human, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Dog, Cow, Horse, Fruit Fly.
How should bs-1849R-Biotin be stored?
Store at -20C for 12 months. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Midkine Polyclonal Antibody, Biotin Conjugated (bs-1849R-Biotin)?
KLH conjugated synthetic peptide derived from mouse Midkine