SPDEF Polyclonal Antibody, RBITC Conjugated

Applications

FCM
IF(IHC-P)
IF(IHC-F)
IF(ICC)

Reactivity

Human
Mouse
Rat

Predicted Reactivity

Dog
Cow
Horse
Chicken
Rabbit

Overview
Catalog #	bs-1866R-RBITC
Product Name	SPDEF Polyclonal Antibody, RBITC Conjugated
Applications	FCM, IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity	Human, Mouse, Rat
Predicted Reactivity	Dog, Cow, Horse, Chicken, Rabbit
Specifications
Conjugation	RBITC
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human PDEF
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID	25803
Subcellular location	Nucleus
Synonyms	bA375E1.3; PDEF; Prostate derived Ets factor; PROSTATE EPITHELIUM SPECIC ETS TRANSCRIPTION FACTOR; Prostate epithelium-specic Ets transcription factor; Prostate specic Ets; Prostate-derived Ets factor; Prostate-specic Ets; PSE; RP11-375E1__A.3; SAM POINTED DOMAIN CONTAINING ETS TRANSCRIPTION FACTOR; SAM pointed domain-containing Ets transcription factor; Spdef; SPDEF_HUMAN.
Background	SPDEF, also known as PDEF is an ETS transcription factor expressed in the prostate epithelial cells. It is thought to act as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter and also as a transcriptional activator for the SERPINB5 promoter. It is highly expressed in prostate carcinoma cells and is thought to be involved in the regulation of the prostate gland and/or prostate cancer development. It is also expressed in epithelial breast carcinoma.
Application Dilution
FCM	1:20-100
IF(IHC-P)	1:50-200
IF(IHC-F)	1:50-200
IF(ICC)	1:50-200

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