MGLUR5 Polyclonal Antibody


  • WB
  • FCM


  • Mouse
  • Rat

Predicted Reactivity

  • Human
  • Cow
  • Sheep
  • Horse
  • Chicken
  • Monkey
Catalog # bs-18801R
Product Name MGLUR5 Polyclonal Antibody
Applications WB, ELISA, FCM
Reactivity Mouse, Rat
Predicted Reactivity Human, Cow, Sheep, Horse, Chicken, Monkey
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human MGLUR5
Immunogen Range 431-530/1212
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID 2915
Swiss Prot P41594
Subcellular location Cell membrane
Synonyms MGLUR5B; Glutamate receptor metabotropic 5; GPRC1E; GRM 5; GRM5; Metabotropic glutamate receptor 5; mGlu5; mGluR5; mGluR5a; mGluR5b; Metabotropic glutamate receptor 5 variant F; Metabotropic Glutamate Receptor 5b; Metabotropic glutamate receptor 5 variant G; Metabotropic glutamate receptor 5 variant H; PPP1R86; GRM5_HUMAN;
Background Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors (mGluRs). Metabotropic Glutamate Receptor 5b (GRM5) activity is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The metabotropic glutamate receptor type 5 (mGlu5) is expressed in two splice variants, mGlu5a and mGlu5b, which differ in that mGlu5b has a 33-amino acid insert in the intracellular C-terminal domain. This receptor subtype is highly regulated, with higher levels found in developing animals.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100